What you'll learn
Knowing the different sources of drug discovery.
Knowing all the different methods of drug optimization and development.
Understanding how drugs function at the molecular level.
Understanding the relationships between physicochemical properties of drugs and their biological activities
Knowing how drugs interact with receptors of different kinds.
Knowing the types of interactions between drugs and receptors.
Be familiar with the modern techniques in the field of drug design such as Computer based methods of QSAR AND Molecular graphics.
Knowing the process of docking using MOE program
Requirements
knowing the basics of pharmaceutical sciences like chemistry
Description
this course is comprehensive as it include all the basics and concepts of drug discovery. After obtaining this course you will be able to easily design your drug from the scratch.if you want to understand the concepts and practice the steps with the most comprehensive Computer-aided drug design course join it now, the course contains theoretical and practical illustration for all concepts of drug discovery.the course is suitable for anyone wants to know and understand the first creation of the drugs and their awesome designing.this course is for anyone wants to learn molecular docking from scratch.the course objectives:Knowing the different sources of drug discovery and lead compound ways.Knowing all the different methods of drug optimization and development.Understanding how drugs function at the molecular level.Understanding the relationships between physico-chemical properties of drugs and their biological activities.Knowing how drugs interact with receptors of different kinds.Knowing the types of interactions between drugs and receptors.Be familiar with the modern techniques in the field of drug design such as: -Computer based methods of quantitative structural activity relationship QSAR. -Molecular graphics.Knowing the process of docking using MOE program.course contents:1.Introduction.2.Sources of lead compound in drug discovery.3.methods of Lead optimization.4.Improvement of drug physiochemical properties.5. Design of drug agonist or antagonist.6.Drug latentiation (prodrug).7.Therapeutic aspects of drug-receptor interaction.8.Structural (steric) features and pharmacological activity.9.Classification of drug active ingredients.10.Quantitative structural activity relationship QSAR.11.Methods used to correlate physicochemical parameters and biological activity.12.Molecular modeling in drug design.13.Docking using MOE program (practical part).
Overview
Lecture 1 course objectives and contents
Lecture 2 Introduction
Section 1: Sources of lead compound in drug discovery
Lecture 3 Sources of lead compound in drug discovery
Section 2: Methods of lead optimization (general and special approaches)
Lecture 4 Methods of lead optimization (general and special approaches)
Section 3: improvement of metabolic properties
Lecture 5 improvement of metabolic properties
Section 4: improvement of absorption
Lecture 6 improvement of absorption
this course is suitable for anyone in the field of pharmacy and drug design such as pharmacists, research and development specialists, chemistry students


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